Yeah, you can exclude it so Windows Defender stops flagging it.
Go to Windows Security > Virus & Threat Protection > Manage settings under "Virus & threat protection settings", then scroll down to Exclusions and click Add or remove exclusions. From there, you can add the specific file, folder, or even the entire software directory.
Just make sure the file is actually safe before excluding it because Defender can be a bit overprotective sometimes, especially with patchers or modded tools.