Way to many ads, the 728x90 at the top are the worst placement ever, if you need to use it put the 728x90 btwn posts or something,and the one in the sidebar is to wide for the sidbars dimensions and overlaps onto the body of the site making it look really bad,especially above the fold like that.
Overall appearance isnt that great either, the header is ok, other then you need a new logo, and rethink you tagline, the tagline makes no sense to me at all.
Also that light blue background behind the body of the site is terrible as well, maybe if it didnt have that wierd light line going thru the middle and just the solid blue it would be better, just use a css gradient or something.