Kloxo needs some tweaks else it overloads most of the times ; trying changing your webserver to nginx or lighttpd , it may help you to take your load down instantly . Update your kloxo to latest version , if going with nginx then install xcache for intact performance , check if your script is using some heavy cron jobs ; schedule them accordingly .
Hope it helps , else throw me a PM i'll help .
Regards
Bharat